Two seemingly disparate men experience powerful life lessons when a wheat harvester gives a hitch-hiking male model a ride on what feels to be the worst day of their lives, at the peak of the war in Vietnam. The harvester has just been diagnosed with cancer, but desperately needs to fulfill a reaping contract, while the male model got himself beaten up in a bar, leading to his firing, and stranding in Kansas.
A research scientist (William Hurt) explores the boundaries and frontiers of consciousness. Using sensory deprivation and hallucinogenic mixtures from native American shamans, he explores these altered states of consciousness and finds that memory, time, and perhaps reality itself are states of mind.
Misery is brought to a small group of Sho in the Kalahari desert in the form of a cola bottle. In his quest to throw the evil object over the edge of the earth, Xixo encounters Western "civilization," a haphazard doctor and a tyranical despot.