Widower Jeevanlal gets arrested for assaulting a Pharmacist as he is unable to afford medicines to treat his ill daughter, Guddu. Subsequently jailed, his repeated and vain attempts to escape only end up increasing his sentence, leaving Guddu to fend on her own. Years later he will re-surface as a wealthy male and prospective Mayor known simply as J.V.; while Guddu will be living two lives - one as the single mother of a young child, Kiran; and the other as a gun-toting alcoholic prostitute known as Bulbul.
It's the lawless future, and renegade biker Harley Davidson (Mickey Rourke) and his surly cowboy buddy, Marlboro (Don Johnson), learn that a corrupt bank is about to foreclose on their friend's bar to further an expanding empire.
An American, Leopold Kessler (Jean-Marc Barr) goes to post-war Germany in 1945 to work as a railroad conductor for the Zentropa Rail Line instead of going into the Army because he feels its a more valuable thing to do for the state of the world.
Whilst on a short weekend getaway, Louise shoots a man who had tried to rape Thelma. Due to the incriminating circumstances, they make a run for it and thus a cross country chase ensues for the two fugitives.