Camille, a naive schoolgirl meets an intiguing influence in Joelle, a slightly older and much more experienced spirit. Camille follows her new friend through the discovery of sex and the darker side of life. As the film progresses Camille discovers Aids and the fear that she may have picked up the disease in her early encounters.
An American, Leopold Kessler (Jean-Marc Barr) goes to post-war Germany in 1945 to work as a railroad conductor for the Zentropa Rail Line instead of going into the Army because he feels its a more valuable thing to do for the state of the world.
Bored with her marriage to burnt out poet turned corporate executive Thierry, Zandalee falls prey to an old friend of her husband, the manipulative and egotistical Johhny and becomes enmeshed in a sensual, passionate and destructive affair.
Amidst her own personality crisis, southern housewife Evelyn Couch meets Ninny, an outgoing old woman who tells her the story of Idgie Threadgoode and Ruth Jamison, two young women who experienced hardships and love in Whistle Stop, Alabama in the 1920s.