Eve, a sensual and dangerous brunette, is the prime suspect in the robbery of information from her boss office. To catch her the boss hires a private dick to find out more details about the double life she leads. The detective discovers that, even though she's a sweet and efficient secretary by day, when night falls she transforms herself into a recruiter of prostitutes to serve the needs of a secret society known as The Golden Phallus. The sect draws the gumshoe to its bordello and it's nefarious matriarch, Maeva.
Professor Phillip Brainard, an absent minded professor, works with his assistant Weebo, trying to create a substance that's a new source of energy and that will save Medfield College where his sweetheart Sara is the president.
The claustrophobic debut of Canadian director Vincenzo Natali takes seven strangers out of their daily lives and places them mysteriously in a deadly cube where they all agree they must find their way out.