As the result of a NASA miscalculation, Astronaut Jack Austin flew to close to the sun, the rays expanding his mind and making him the smartest man on the planet. Now he and his talking motorcycle (who contains the mind of his former roommate) are on the run from NASA and their assain, actor Ron Silver who want to take his brain. They travel from place to place solving paranormal mysteries with the help of Jack's newfound ability to become a super genius when his brain absorbs sunlight.
Homer is an orphan who was never adopted, becoming the favorite of orphanage director Dr. Larch. Dr. Larch imparts his full medical knowledge on Homer, who becomes a skilled, albeit unlicensed, physician.
Rookie cop Amelia Donaghy reluctantly teams with Lincoln Rhyme -- formerly the department's top homicide detective but now paralyzed as a result of a spinal injury -- to catch a grisly serial killer dubbed The Bone Collector.
Following a bomb scare in the 1960s that locked the Webers into their bomb shelter for 35 years, Adam now ventures forth into Los Angeles to obtain food and supplies for his family, and a non-mutant wife for himself.