Manu has lived a difficult life. Abused and violently raped, she sets off to find herself only to meet Nadine, a prostitute who has encountered one too many injustices in the world. Angry at the world, they embark on a twisted, rage-filled road trip. They choose to have sex when they please and kill when they need. Leaving a trail of mischief and dead bodies in their wake. Generating a media blitz and manhunt, soon everyone is out to capture the young fugitives.
Diana is a Roman wife happily married to sympathetic Paolo but she is keen on playing benign games of seduction with other men while resisting the advances of chic lingerie shop owner Silvio and she narrates her adventures to Paolo in order to stimulate their otherwise monotonous sexual life.
Brooklyn mobster and prolific hit man Jimmy Conlon has seen better days. Longtime best friend of a mob boss, Jimmy is haunted by the sins of his past—as well as a dogged police detective who’s been one step behind Jimmy for 30 years.
Bored and restless, Alice spends much of her time lusting after Jim, a local sawmill worker. When not lusting after him, Alice fills the hours with such pursuits as writing her name on a mirror with vaginal secretions and wandering the fields with her underwear around her ankles.
When record store owner Rob Gordon gets dumped by his girlfriend, Laura, because he hasn't changed since they met, he revisits his top five breakups of all time in an attempt to figure out what went wrong.