Kaala Varkey movie is about Varkey ( Jagathy Sreekumar) who is a crude and brazen man. The locals call him ‘kaala’ Varkey ( kaala means bull), as he is a man who cares more for his bulls than his wife Annamma (Pallavi) and three daughters Alice (Suvarna Mathew), Sophia (Meenakshi) and Lisy (Krishnendu). But in an accident Varkey becomes bedridden and a guy from another village, Jose (Vijayaraghavan) comes to look after the bulls. This man arrives with some purpose and his aim is to see the downfall of Varkey.
Vampires and werewolves have waged a nocturnal war against each other for centuries. But all bets are off when a female vampire warrior named Selene, who's famous for her strength and werewolf-hunting prowess, becomes smitten with a peace-loving male werewolf, Michael, who wants to end the war.
After a misunderstanding aboard an airplane that escalates out of control, the mild-mannered Dave Buznik is ordered by Judge Daniels to attend anger management sessions run by Doctor Buddy Rydell, which are filled with highly eccentric and volatile men and women.