Kitagawa and Shizu are lovers and roommates. Suffering from a panic disorder, Kitawgawa estranges himself from the world and entraps himself in the claustrophobic confines of the apartment. He leaves only to attend his new seminar. Initially heartened by his interest in this new venture, Shizu senses something fishy when he shows up with a strange amulet and begins to fill their place with unfamiliar furniture. When he commences rambling about the karmic life, she realizes that the man she cares for has become a complete stranger.
After five (or six) years of vanilla-wedded bliss, ordinary suburbanites John and Jane Smith (Pitt and Jolie) are stuck in a rut the size of the Grand Canyon?until the truth comes out! Unbeknownst to each other, they are both coolly lethal, highly paid assassins working for rival organizations.
Constantine tells the story of John Constantine, a man who has literally been to Hell and back. When he teams up with a policewoman to solve the mysterious suicide of her twin sister, their investigation takes them through the world of demons and angels that exists beneath the landscape of contemporary Los Angeles.