Elizabeth and Tom Schubert are going through a marital crisis due to jealousy of him. They decide given a new opportunity and travel to Phuket in Thailand, where they expected Julia, a friend of Elizabeth to that Tom does not support. The couple had a heated argument and she decides to leave with Julia for a few days, a period in which lives a romance with an attractive architect.
As the war between the vampires and the Lycans rages on, Selene, a former member of the Death Dealers (an elite vampire special forces unit that hunts werewolves), and Michael, the werewolf hybrid, work together in an effort to unlock the secrets of their respective bloodlines.
When he loses a highly publicized virtual boxing match to ex-champ Rocky Balboa, reigning heavyweight titleholder Mason Dixon retaliates by challenging the Itallian Stallion to a nationally televised, 10-round exhibition bout.