After having suffered a serious car accident in which his 6 month pregnant wife is killed, X, a 35 year old man, is admitted in an intensive care unit. K, a 30 year old nurse, will help X during his rehabilitation. K is also 6 months pregnant. This curious detail makes their apparent impersonal relationship stronger.
For Nick (Jason Bateman), Kurt (Jason Sudeikis) and Dale (Charlie Day), the only thing that would make the daily grind more tolerable would be to grind their intolerable bosses (Kevin Spacey, Colin Farrell, Jennifer Aniston) into dust.
A cop (Matthew McConaughey) who moonlights as a hit man agrees to kill the hated mother of a desperate drug dealer (Emile Hirsch) in exchange for a tumble with the young man's virginal sister (Juno Temple).
A fisheries expert is approached by a consultant to help realize a sheik's vision of bringing the sport of fly-fishing to the desert and embarks on an upstream journey of faith and fish to prove the impossible possible.