On Christmas day, a bomb explodes in a shopping mall. The explosion was perpetrated by a serial bomber. A 9-year-old boy Kuro Hazama and his mother Mitsuko (Naho Toda) are seriously and transfered to a university hospital. With the elite skills of surgeon Dr. Jontaro Honma (Masachika Ichimura), Kuro survives, but is shocked to learn his mother is in a coma. Dr. Honma tells Tokio that when medical science advances, Michiko might one day awake. Tokio decides then to become a doctor. 15 years later, 24-year-old Kuro is a medical student and his mother is still in a coma. Kuro researches ways to awaken his mother whilst practising medicine without a licence.
There is a new criminal mastermind at large--Professor Moriarty--and not only is he Holmes’ intellectual equal, but his capacity for evil and lack of conscience may give him an advantage over the detective.
For Nick (Jason Bateman), Kurt (Jason Sudeikis) and Dale (Charlie Day), the only thing that would make the daily grind more tolerable would be to grind their intolerable bosses (Kevin Spacey, Colin Farrell, Jennifer Aniston) into dust.
In an alternate world, humanity and vampires have warred for centuries. After the last Vampire War, the veteran Warrior Priest lives in obscurity with other humans inside one of the Church's walled cities.
Hugo is an orphan boy living in the walls of a train station in 1930s Paris. He learned to fix clocks and other gadgets from his father and uncle which he puts to use keeping the train station clocks running.