A strange phenomenon takes place. A beautiful flower blooms on a selected woman's body and that flower is called the "Shanidar". When the Shanidar is in full bloom, the flower produces a substance which is then sold at a high cost to develop new drugs. Kenji Otaki (Gou Ayano) works as a researcher at the facility where the Shanidar is grown.
Jack Harper (Tom Cruise) is one of the last few drone repairmen stationed on Earth. Part of a massive operation to extract vital resources after decades of war with a terrifying threat known as the Scavs, Jack’s mission is nearly complete.
Iconoclastic, take-no-prisoners cop John McClane, finds himself for the first time on foreign soil after traveling to Moscow to help his wayward son Jack - unaware that Jack is really a highly-trained CIA operative out to stop a nuclear weapons heist.