A scientist searches for answers to his son's mysterious death in the Algerian desert, and discovers a vortex of unexplained activity similar to the Bermuda Triangle. His investigation uncovers eleven other "Vile Vortices" around the world, where some of the planet's most unusual and disturbing events are taking place. Bizarre animal attacks, unexplained weather patterns, and passenger jets disappearing right out of the sky might only be the beginning of a greater, looming threat.
When the magic powers of The Tablet of Ahkmenrah begin to die out, Larry Daley (Ben Stiller) spans the globe, uniting favorite and new characters while embarking on an epic quest to save the magic before it is gone forever.
The story of a super-secret spy organization that recruits an unrefined but promising street kid into the agency's ultra-competitive training program just as a global threat emerges from a twisted tech genius.