In the small Caribbean island of St. Lucia lives an ancient spirit. Soucouyant, as she is known, cannot be contained, captured or killed. The people in the town of Gros Islet have come face to face with this reality. Soucouyant has taken 8 lives already when she prepares for her latest victim. As she passes through the town her spirit begins the task of finding a replacement for her tortured skin.
Thrust into an all-new adventure, a down-on-his-luck Captain Jack Sparrow finds the winds of ill-fortune blowing even more strongly when deadly ghost pirates led by his old nemesis, the terrifying Captain Salazar (Bardem), escape from the Devil's Triangle, determined to kill every pirate at sea.
Assassin Robert Rath (Sylvester Stallone) arrives at a funeral to kill a prominent mobster, only to witness rival hired gun Miguel Bain (Antonio Banderas) complete the job for him -- with grisly results.
The story revolves around the passengers of a yachting trip in the Atlantic Ocean who, when struck by mysterious weather conditions, jump to another ship only to experience greater havoc on the open seas.
An extremely wealthy elderly man dying from cancer undergoes a radical medical procedure that transfers his consciousness to the body of a healthy young man but everything may not be as good as it seems when he starts to uncover the mystery of the body's origins and the secret organization that will kill to keep its secrets.