Fresh out of college, Barry the Bee (Jerry Seinfeld) finds the prospect of working with honey uninspiring. He flies outside the hive for the first time and talks to a human (Renée Zellweger), breaking a cardinal rule of his species. Barry learns that humans have been stealing and eating honey for centuries, and he realizes that his true calling is to obtain justice for his kind by suing humanity for theft.
After her outlaw husband returns home shot with eight bullets and barely alive, Jane reluctantly reaches out to an ex-lover who she hasn't seen in over ten years to help her defend her farm when the time comes that her husband's gang eventually tracks him down to finish the job.
After supervillain Shredder (Brian Tee) escapes custody, he joins forces with mad scientist Baxter Stockman (Tyler Perry) and two dimwitted henchmen, Bebop (Gary Anthony Williams) and Rocksteady (Stephen "Sheamus" Farrelly), to unleash a diabolical plan to take over the world.