One late afternoon, a mysterious guy tries to hitchhike in the middle of nowhere. But nobody seems to give him a ride. It is getting quite dark, a small van driver suddenly stops his car because he saw a man standing in front of his vehicle and the strange guy gets in the car abruptly.
New York City is full of lonely hearts seeking the right match, and what Alice, Robin, Lucy, Meg, Tom and David all have in common is the need to learn how to be single in a world filled with ever-evolving definitions of love.
The epic story of the first contact, encounter, approach, betrayal and, eventually, life-transcending friendship, between Karamakate, an Amazonian shaman, last survivor of his people, and two scientists that, over the course of 40 years, travel through the Amazon in search of a sacred plant that can heal them.