Summer time. Two teenagers, a boy and a girl, have their first date in a park. Hesitant and shy at first, they soon discover each other, get closer as they wander, and end up falling in love. But as the sun goes down, it is time to separate... And a dark night begins.
There are many things in life that could do a number on a man's masculinity. Lenny Babbitt has his identity and manhood challenged when his wife Tracy leaves him for a female doctor named Iris who has been treating their autistic son Isaac.
The epic story of the first contact, encounter, approach, betrayal and, eventually, life-transcending friendship, between Karamakate, an Amazonian shaman, last survivor of his people, and two scientists that, over the course of 40 years, travel through the Amazon in search of a sacred plant that can heal them.