The story picks up from Part 1 as Enoken's young scion forsakes his wealth and takes a department store job – in drag and sometimes blackface – to prove to the girl of his dreams that he be a hard-working, serious man.
Film portrays the expedition of the British explorer David Livingstone to Africa to discover the source of the Nile, his disappearance, and the expedition to find him led by Stanley.
Chet Kasedon is after the Indians hidden gold mine but Chief Moya will not reveal it's location. He has also hired mining engineers Gale and Mortimer to locate the mine.
Although Larry "Buster" Crabbe earns top billing, the hero of Drift Fence is former Western star Tom Keene as Jim Travis, who, at a rodeo, meets city dweller Jim Traft, who has come west to erect a fence that will prevent Clay Jackson from continuing his cattle rustling business.
This short follows the early career of actress Jane Barnes. She starts by doing extra work. After several months she is offered a studio contract (the "first step").