Four unwitting heroes cross paths on their journey to the sleepy town of Silverado. Little do they know the town where their family and friends reside has been taken over by a corrupt sheriff and a murderous posse.
In 1890, the year of the U.S. census, chaos erupts when a stranger named Strindler arrives in a small town in Arizona and requests money for providing the names of dead Mexican laborers.
The Sherrif of a small Western town witnesses a sickness quickly overtaking the locals. Along with his trusty Deputy Carl and plucky sidekick Annie they try to save the town.
Chicago hotel clerk Frank Harris dreams of life as a cowboy, and he gets his chance when, jilted by the father of the woman he loves, he joins Tom Reece and his cattle-driving outfit.
Learning that Montana is about to become a state and that property values will rise rapidly, Caldwell is using his outlaw gang to force the ranchers off their land.
Carrie Snyder is a prostitute, who is forced out of the fictional southern town of Crebillon, after forming a friendship with a young boy named Paul, whose dying mother is unable to protest against her son visiting such a woman.
In London, August 1914, Austrian star Elsa Duranyi (Gertrude Michael) and English matinee idol Alan Barclay (Herbert Marshall) are in love and plan an immediate marriage.
Frankie Reynolds (Frankie Darro' ), youngest member of a family of jockeys, borrows $4.85 (yes, four dollars and eighty-five cents) from his sister Phyllis (Gladys Blake), who is not a jockey, to buy a crippled colt from the stables owned by Clay Harrison (Kane Richmond).
Paddy O'Riley and Ossie Merrill, Bellport high school football heroes, enroll in distant colleges; Paddy at a small school in the East, where he is barely a substitute, and Ossie at a powerhouse-football school, where he is an instant star and all-American candidate.