Although Larry "Buster" Crabbe earns top billing, the hero of Drift Fence is former Western star Tom Keene as Jim Travis, who, at a rodeo, meets city dweller Jim Traft, who has come west to erect a fence that will prevent Clay Jackson from continuing his cattle rustling business.
Film portrays the expedition of the British explorer David Livingstone to Africa to discover the source of the Nile, his disappearance, and the expedition to find him led by Stanley.
In 1921, British Lord Athleigh arrives in Dublin with his daughter, Helen, to engage in peace talks. As wanted Irish rebel leader Dennis Riordan is not recognized in public, he is able to move about freely and saves the Athleighs from an assassination attempt by a radical faction.