Farmer Al Falfa and Puddy's farm is shriveling up under the intense heat. A peddler provides magic explosive pills that cause it to rain, and the crops swell up instantly. Unfortunately, it's all a dream.
A bumbling tramp desires to build a home with a young woman, yet is thwarted time and time again by his lack of experience and habit of being in the wrong place at the wrong time.
Hoping to rid a small western community of its corrupt political machine, Ken Marshall (Ken Maynard) runs for sheriff against the bad guys' candidate and wins the election.
A retired Scotland Yard detective, Patrick Fitzpatrick (Tom Walls) comes back to take one final case, tracking down a missing vase which has been stolen by a gang of thieves specialising in taking art treasures.
Confederate Col. Lafe Harvey (Earl Ross) travels home after the Civil War, where he must tell his niece, Betty (Frances Grant), that her father is presumed dead.
Although Larry "Buster" Crabbe earns top billing, the hero of Drift Fence is former Western star Tom Keene as Jim Travis, who, at a rodeo, meets city dweller Jim Traft, who has come west to erect a fence that will prevent Clay Jackson from continuing his cattle rustling business.
Carrie Snyder is a prostitute, who is forced out of the fictional southern town of Crebillon, after forming a friendship with a young boy named Paul, whose dying mother is unable to protest against her son visiting such a woman.
Film portrays the expedition of the British explorer David Livingstone to Africa to discover the source of the Nile, his disappearance, and the expedition to find him led by Stanley.