When a band of American Indians breaks a treaty with the federal government, U.S. Marshals Ken Maynard and Hoot Gibson hit the trail with captured outlaw Duke Dillon (Jack La Rue) to find out what sparked the uprising.
Nicoletta is a young rebel, cherished by his forgiving father, until an old relative joins the family after the wedding of her sister, and insists that the impetuous girl is sent to college.
Deerslayer, a white man who was brought up by the Mohicans, helps his old tribe when the Hurons steal Princess Wah Tah, the betrothed of his friend Jingo-Good.
Tex Wyatt is blamed for a murder actually committed by Ransom and Holman, a couple of thieves. Tex manages to escape and is reunited with his two ranger pals Jim Steele and Panhandle Perkins, both of whom are working undercover as performers in a medicine show.
A group of cowboys ending their cattle drive in Abilene find that cattle prices are being kept artificially low, driving down the price they'll get for their beef.