Near Border Flats, Don Coyote and his friend Sancho are interrupted on their way to the fiesta by a fight. A quick intervention on their part prompts ranch owner Maggie Riley to hire them. Coyote and Sancho meet her surly, younger brother Ted who is wanting Maggie to sell their cattle herd to pay off a bank loan before they lose the ranch. But when they try to drive a herd to market, a gang led by Big Foot Ferguson drives off their cowhands.
Ranger Eddie Dean is looking for the outlaw the Tioga Kid, a man he closely resembles. He runs into Joe Morino and his gang of rustlers at the same time Tioga arrives to cut himself into Morino's game.
James Kincaid controls the local water supply and plans to do away with the other ranchers. Government agent Sandy Saunders arrives undercover to investigate Kincaid's land swindle scheme, and win the heart of one of his victims, Fay Denton.
In the midst of the Civil War, Lassiter has a plan to get control of California. Working out of St. Joseph, he plans to send forged messages to the troops on the west coast via Pony Express.
The Sheriff and his deputies are after Scar Adams. Scar is the brother of Alice Denton, the girl Deputy Tom plans to marry, and when the Sheriff is wounded she makes Tom refuse the job of Sheriff.
Convicted killer Jim Holden is rescued from the sheriff by his gang, led by Mason and Riley. He is out to get the Hathaway Stage superintendent George Bannister, who was responsible for his conviction and learns the Bannister, his niece (Kay) and Hal Hathaway, son of the stage line owner, are on a cross-country stage.
A hated country gentleman is murdered, and the inspector on the case takes the veiwer through his thoughts about the possible murderer and motives as he questions everyone concerned.
Maggi continues her forever-ever efforts to crash Manhattan's top society, while Jiggs still mingles with his old construction cronies at the bar of Dinty Moore on 10th Avenue.
