The activities of the National Technical Institute are presented, which played an important role in raising technical culture and knowledge in the years after liberation.
In Milan, the beggar Carlone has formed a brotherhood. Carlone's sister Anna, is a poor blind girl. One day Carlone saves a mutilated, who tried to end his days.
A traveler arrives at the Usher mansion to visit his old friend, Roderick Usher. Upon arriving, however, he discovers that Roderick and his sister, Madeline, have been afflicted with a mysterious malady: Roderick's senses have become painfully acute, while Madeline has become nearly catatonic.
Young swain Toto Esposito tries to abduct his beloved to marry her, but he makes a mistake: he kidnaps an ugly woman named Carmela, who loves him--and chases him when he escapes.
Notorious stagecoach robber Rhiannon is unintentionally appointed as deputy when he saves the sheriff's life and must wear two hats between his new job that he enjoys and his old occupation that he misses.
The Durango Kid rides again in Lightning Guns. As ever, the masked Durango (alias Steve Brandon) is played by Charles Starrett, who this time around is on the trail of a gang of cold-blooded killers.