Skin and Bones gently introduce us to the world of anorexia and bulimia. The heroines of this moving film in which reality and fiction merge are called Annie, Andréanne, Hélène, Eisha.
A St. Louis cop, Mike Braxton (Sam Jones), receives an urgent call for help from his brother Tony (Nick Cassavetes), a small time thief in Los Angeles.
A naive young man from the countryside moves to the big city to study art. Soon he has some strange experiences: His roommate turns out to be the bodyguard-protected son of a mafia boss, his fellow student is desperate to initiate him into love, and his attractive art professor also seems to have it in for him.