Whilst on a short weekend getaway, Louise shoots a man who had tried to rape Thelma. Due to the incriminating circumstances, they make a run for it and thus a cross country chase ensues for the two fugitives.
This bizarre surrealistic black comedy takes place in a small fictitious post-apocalyptic town where food is scarce and butcher Clapet has the macabre business of using human flesh to feed his customers.
George Banks is an ordinary, middle-class man whose 21 year-old daughter Annie has decided to marry a man from an upper-class family, but George can't think of what life would be like without his daughter.
Amidst her own personality crisis, southern housewife Evelyn Couch meets Ninny, an outgoing old woman who tells her the story of Idgie Threadgoode and Ruth Jamison, two young women who experienced hardships and love in Whistle Stop, Alabama in the 1920s.