An old man gets lost looking for a post office. Every time he turns around a street corner, he ends up in the same small café. The café owner builds an ice sculpture of the woman he admires.
A technical problem aboard a transatlantic flight forces a plane to land in Porto Santo, the small island of Madeira's archipelago where, according to a legend, Christopher Columbus the 15th century navigator, lived for a while and entertained a sexual relationship with a widow and her nubile daughter.
A patient dies beneath Dr. Robert Stenzel's hands. His wife, the virologist Simone, realizes too late that the deceased was carrying a contagious virus.
The Director reflects upon and seeks to understand the causes and the events that lead to her drug-addicted prostitute daughter being murdered at the age of 26.