A series of "vampire" style murders on campus has Sarah scared of her own shadow - It doesn't help that her new dorm mate Lilith wears only gothic clothing, is afraid of crosses, avoids daylight and resembles a member of the undead. Sarah becomes convinced that Lilith has something to do with the horrendous murders. When Sarah can't convince others of her outlandish theory...she becomes the next target.
A rare mutation has occurred within the vampire community - The Reaper. A vampire so consumed with an insatiable bloodlust that they prey on vampires as well as humans, transforming victims who are unlucky enough to survive into Reapers themselves.
The story of how a mysterious suitcase brings together, and changes, the lives of a divorced dad, an unhappy housewife, two hitmen, a pair of street thugs, two love struck teens, two FBI men and a psychedelic toad.
Kay and Jay reunite to provide our best, last and only line of defense against a sinister seductress who levels the toughest challenge yet to the MIB's untarnished mission statement – protecting Earth from the scum of the universe.