With the impending ice age almost upon them, a mismatched trio of prehistoric critters – Manny the woolly mammoth, Diego the saber-toothed tiger and Sid the giant sloth – find an orphaned infant and decide to return it to its human parents.
A rare mutation has occurred within the vampire community - The Reaper. A vampire so consumed with an insatiable bloodlust that they prey on vampires as well as humans, transforming victims who are unlucky enough to survive into Reapers themselves.
Tenacious homicide detective Cassie Mayweather and her still-green partner are working a murder case, attempting to profile two malevolently brilliant young men: cold, calculating killers whose dark secrets might explain their crimes.
Mike Sullivan works as a hit man for crime boss John Rooney. Sullivan views Rooney as a father figure, however after his son is witness to a killing, Mike Sullivan finds himself on the run in attempt to save the life of his son and at the same time looking for revenge on those who wronged him.
It's 1863. America was born in the streets. Amsterdam Vallon returns to the Five Points of America to seek vengeance against the psychotic gangland kingpin, Bill the Butcher, who murdered his father years earlier.