When a boy is too confused to speak with his non-communicative family, words eventually lose their meaning. He decides to communicate with his dandruff and a cup of cold coffee instead. His father ignores these eccentricities, assuming it is just a ploy to get attention. Meanwhile, the boy's sister likes exercising seductively in front of men and is better able to capture her father's attention than her brother. Their mother is oblivious, perpetually talking to people on her mobile phone and the space the family occupies grows narrower and narrower.
After a misunderstanding aboard an airplane that escalates out of control, the mild-mannered Dave Buznik is ordered by Judge Daniels to attend anger management sessions run by Doctor Buddy Rydell, which are filled with highly eccentric and volatile men and women.
A tale which follows the comedic and eventful journeys of two fish, the fretful Marlin and his young son Nemo, who are separated from each other in the Great Barrier Reef when Nemo is unexpectedly taken from his home and thrust into a fish tank in a dentist's office overlooking Sydney Harbor.
Chris crashes into a carload of other young people, and the group of stranded motorists is soon lost in the woods of West Virginia, where they're hunted by three cannibalistic mountain men who are grossly disfigured by generations of inbreeding.