Vampires and werewolves have waged a nocturnal war against each other for centuries. But all bets are off when a female vampire warrior named Selene, who's famous for her strength and werewolf-hunting prowess, becomes smitten with a peace-loving male werewolf, Michael, who wants to end the war.
After 23 horrifying days of gorging on human flesh, an ancient creature known as the Creeper embarks on a final voracious feeding frenzy, terrorizing a group of varsity basketball players, cheerleaders and coaches stranded on a remote highway when their bus breaks down.
Jerry Falk, an aspiring writer in New York, falls in love at first sight with a free-spirited young woman named Amanda He has heard the phrase that life is like "anything else," but soon he finds that life with the unpredictable Amanda isn't like anything else at all.
Chris crashes into a carload of other young people, and the group of stranded motorists is soon lost in the woods of West Virginia, where they're hunted by three cannibalistic mountain men who are grossly disfigured by generations of inbreeding.