In the 1920s, former coal miner Harry Hoxsey claimed to have an herbal cure for cancer. Although scoffed at and ultimately banned by the medical establishment, by the 1950s, Hoxsey's formula had been used to treat thousands of patients, who testified to its efficacy.
In 1960s Wyoming, two men develop a strong emotional and sexual relationship that endures as a lifelong connection complicating their lives as they get married and start families of their own.
John Constantine has literally been to Hell and back. When he teams up with a policewoman to solve the mysterious suicide of her twin sister, their investigation takes them through the world of demons and angels that exists beneath the landscape of contemporary Los Angeles.
The single mother Leonie has great worries: Since her ex-boyfriend left her a huge debt mountain, knows the young cosmetics saleswoman hardly how to make a living.