Dakota, a young werewolf, has finally learned to control her nighttime transformations. She desperately wants to live a normal life, and to break free from her curse, she flees to hide in the city. When the pack aggressively hunts her down, the bouncers offer her protection and band together to battle the werewolves who want her dead... and who won't give up their wolf without a vicious fight.
London high-society mouse, Roddy is flushed down the toilet by Sid, a common sewer rat. Hang on for a madcap adventure deep in the sewer bowels of Ratropolis, where Roddy meets the resourceful Rita, the rodent-hating Toad and his faithful thugs, Spike and Whitey.
Chaos reigns at the natural history museum when night watchman Larry Daley accidentally stirs up an ancient curse, awakening Attila the Hun, an army of gladiators, a Tyrannosaurus rex and other exhibits.
Le Chiffre, a banker to the world's terrorists, is scheduled to participate in a high-stakes poker game in Montenegro, where he intends to use his winnings to establish his financial grip on the terrorist market.
In 2027, in a chaotic world in which humans can no longer procreate, a former activist agrees to help transport a miraculously pregnant woman to a sanctuary at sea, where her child's birth may help scientists save the future of humankind.
As the war between the vampires and the Lycans rages on, Selene, a former member of the Death Dealers (an elite vampire special forces unit that hunts werewolves), and Michael, the werewolf hybrid, work together in an effort to unlock the secrets of their respective bloodlines.