Cold-hearted professor Dominique is suffering from kidney failure. While attending the Smith and Wesson family reunion, she tries to approach estranged sister, CeCe, for a transplant. However, the two of them have too many unresolved issues from their childhood. At great emotional expense, CeCe tries to confront past demons to find forgiveness and healing. Struggling with her own vulnerability, Dominique is forced to do some soul searching to address personal shortcomings in order to save her own life. And as the events surrounding the reunion continue to unfold, family members uncover buried truths and love, yet family politics nevertheless persist with the Smiths vying to maintain dominance and shut out the Wesson faction.
During a trip to Germany to scatter their grandfather's ashes, German-American brothers Todd and Jan discover Beerfest, the secret Olympics of downing stout, and want to enter the contest to defend their family's beer-guzzling honor.
Mexican beauty Camilla hopes to rise above her station by marrying a wealthy American. That is complicated by meeting Arturo Bandini, a first-generation Italian hoping to land a writing career and a blue-eyed blonde on his arm.
FBI agent Malcolm Turner goes back undercover as Big Momma, a slick-talking, slam-dunking Southern granny with attitude to spare! Now this granny must play nanny to three dysfunctional upper class kids in order to spy on their computer hacked dad.
Jigsaw has disappeared. Along with his new apprentice Amanda, the puppet-master behind the cruel, intricate games that have terrified a community and baffled police has once again eluded capture and vanished.
A man receives a mysterious e-mail appearing to be from his wife, who was murdered years earlier. As he frantically tries to find out whether she's alive, he finds himself being implicated in her death.