Eight years have passed since Sara Wolfe and Eddie Baker escaped the House on Haunted Hill. Now the kidnapped Ariel, Sara's sister, goes inside the house with a group of treasure hunters to find the statue of Baphomet, worth millions and believed to be the cause of the House's evil.
An ancient urn is found in a cemetery outside Rome. Once opened, it triggers a series of violent incidents: robberies, rapes and murders increase dramatically, while several mysterious, evil-looking young women coming from all over the world are gathering in the city.
A Texas cop (Kevin Kline), whose own daughter might have been forced into sexual slavery, joins forces with a Mexican youth (Cesar Ramos) to find the boy's sister, who was abducted and forced into prostitution.