Comanche Moon, the prequel to McMurtry's bestselling and Pulitzer Prize-winning book, "Lonesome Dove follows Texas Rangers Augustus "Gus" McCrae (Zahn) and Woodrow F. Call (Urban), now in their middle years, as they continue to deal with the ever-increasing tensions of adult life--Gus with his great love, Clara Forsythe (Cardellini), and Call with Maggie Tilton (Banks), the young prostitute who loves him and bears him his son, Newt (Joseph Castanon). Kilmer plays Captain Inish Scull, a Yankee aristocrat and hero of the recently concluded Mexican War. Griffiths plays Inez Scull, the Captain's sexy wife who doesn't hesitate to fill her time with other men when he's away from home. Wes Studi plays Comanche Chief Buffalo Hump.
Cultural critic David Kepesh finds his life -- which he indicates is a state of "emancipated manhood" -- thrown into tragic disarray by Consuela Castillo, a well-mannered student who awakens a sense of sexual possessiveness in her teacher.
Guinevere Pettigrew, a middle-aged London governess, finds herself unfairly dismissed from her job. An attempt to gain new employment catapults her into the glamorous world and dizzying social whirl of an American actress and singer, Delysia Lafosse.
Six years after the events of The X-Files series finale, former FBI agent Doctor Dana Scully is now a staff physician at Our Lady of Sorrows, a Catholic hospital, and treating a boy named Christian who has Sandhoff disease, a terminal brain condition.