Aliens land in South Africa and, with their ship totally disabled, have no way home. Years later, after living in a slum and wearing out their welcome the 'Non-Humans' are being moved to a new tent city overseen by Multi-National United (MNU).
From the Egyptian desert to deep below the polar ice caps, the elite G.I. JOE team uses the latest in next-generation spy and military equipment to fight the corrupt arms dealer Destro and the growing threat of the mysterious Cobra organization to prevent them from plunging the world into chaos.
The story revolves around the passengers of a yachting trip in the Atlantic Ocean who, when struck by mysterious weather conditions, jump to another ship only to experience greater havoc on the open seas.
B-Dawg, Mudbud, Budderball, and all the rest of the Buddies are back, but this time, they're setting their sights even higher -- as in, the moon! With the help of their new pals Spudnick (voiced by Jason Earles) and Gravity, these pooches are go for launch.
Famous and wealthy funnyman George Simmons doesn't give much thought to how he treats people until a doctor delivers stunning health news, forcing George to reevaluate his priorities with a little help from aspiring stand-up comic Ira.