After the fall of Shadaloo, things went quiet and everyone continued with their daily routine. However a new evil is lurking on the horizon and the fighters that battled against Shadaloo must take up arms once again. Meanwhile a mysterious detective, whose motives are unknown, is going to any extent to find the lonesome wanderer Ryu, who appears to play a big part in the scheme of this new evil.
When a virus leaks from a top-secret facility, turning all resident researchers into ravenous zombies and their lab animals into mutated hounds from hell, the government sends in an elite military task force to contain the outbreak.
An American teenager who is obsessed with Hong Kong cinema and kung-fu classics makes an extraordinary discovery in a Chinatown pawnshop: the legendary stick weapon of the Chinese sage and warrior, the Monkey King.
The four turtles travel back in time to the days of the legendary and deadly samurai in ancient Japan, where they train to perfect the art of becoming one.
As the city is locked down under quarantine, Alice finds out that the people that died from the previous incident at the Umbrella Corporation have turned into zombies.
The Turtles and the Shredder battle once again, this time for the last cannister of the ooze that created the Turtles, which Shredder wants to create an army of new mutants.
A vicious genetically modified creature that's half human and half dire wolf escapes from a research facility so it can go on a murderous rampage in a quiet rural community.
Dr. Adrian Helmsley, part of a worldwide geophysical team investigating the effect on the earth of radiation from unprecedented solar storms, learns that the earth's core is heating up.