"Have you ever dreamt of a better version of yourself?" 18 September 2024 Horror, Sci-Fi 141 mins
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Watch the official The Substance 2024 trailer in HD below.
Demi Moore as Elisabeth
Margaret Qualley as Sue
Dennis Quaid as Harvey
Edward Hamilton-Clark as Fred
Gore Abrams as Oliver
Oscar Lesage as Troy
Christian Erickson as Man at Diner
Tom Morton as Doctor
Hugo Diego Garcia as Diego - Boyfriend
Daniel Knight as Casting Director
Jonathon Carley as Assistant Casting Director
Akil Wingate as TV Host
Vincent Colombe as Man in Suit #1 - Harvey's Office
Lennard Ridsdale as Man in Suit #3
Jordan Ford Silver as Assistant Director - Pump It Up Show
Oscar Salem as 2nd Assistant Director - Pump It Up Show
Matthieu de la Mortière First Assistant Director
Anne Juin Third Assistant Director
Erik Baiers Executive Producer
Stanislas Reydellet Production Design
Benjamin Kračun Director of Photography
Jérôme Eltabet Editor
Cécilia Blom Set Decoration
Frédéric Balmer Special Effects Makeup Artist
Denise Boccacci Prosthetic Makeup Artist
Andrea Leanza Prosthetics Sculptor
Sebastian Lochmann Concept Artist
Richard Martin Prosthetics Sculptor
Krystell Morantin Assistant Art Director
Bryan Jones Visual Effects Supervisor
Marie Bouvet Stunt Double
Jérôme Gaspard Stunt Coordinator
Սուբստանցիա Trailer
La Substance Trailer
სუბსტანცია Trailer
サブスタンス Trailer
substancja Trailer
Cevher Trailer
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United States 01 October 2026
Virgin Islands (U.S.) 10 October 2025
Viet Nam 29 March 2025
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Have you watched The Substance yet? What did you think about it?
Artwork, screen shots, trailers and other imagery is © 2024 Working Title, Working Title Films, Blacksmith.