Dalton, a promising young doctor, becomes infatuated with a dancer named La Stella who introduces him to drugs, and he becomes a morphine addict. His addiction leads to the death of a child due to a fatal medical error while he is under the influence, ultimately ruining his career.
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Mark Stetson, a scheming politician, entangles the Brandons, husband and wife, and their friend, Antoinette, in his smuggling schemes and engineers their arrest, to protect himself.
Irving Lawrence owns some of the most decrepit tenements in town and is an all-around bad guy. He won't cooperate with the efforts of his wife, Barbara, to help the poor and sees other women behind her back.
A banker, after a prophetic meeting with a Gypsy fortune teller, becomes delusional as he searches for a trunk which the seer has told him holds the key to either his happiness or his death.
Margot Sperry, who keeps house for her guardian, a professor who wants to revert to primitive modes of living, finds it difficult to find food in the winter wilderness and resorts to pilfering from the Bates's winter camp.
Lord John, a detective novelist and the Marquis of Haslemere's brother, receives word that the stage adaption of one of his stories will not be performed because Roger Odell, a millionaire, has spoken against him.
Emphasizing themes of female independence and the esteem due to the men serving in the armed forces, the plot involves a strong-willed young woman (Agnes Vernon) who defies her father in order to marry a soldier (Hobart Henly) instead of the well-to-do suitor preferred by her father.
Movie mogul Thomas H. Ince may well have been the director of The Despoiler as indicated by the credits; but since Ince was known far and wide as a glory-hogger, it's also possible that one of his talented lieutenants wielded the megaphone.
A man neglects his wife to be with a dance hall singer. When the truth of his infidelity reaches his wife and the truth of his marital status reaches his lover, both women are heartbroken.