Although Larry "Buster" Crabbe earns top billing, the hero of Drift Fence is former Western star Tom Keene as Jim Travis, who, at a rodeo, meets city dweller Jim Traft, who has come west to erect a fence that will prevent Clay Jackson from continuing his cattle rustling business.
In 1921, British Lord Athleigh arrives in Dublin with his daughter, Helen, to engage in peace talks. As wanted Irish rebel leader Dennis Riordan is not recognized in public, he is able to move about freely and saves the Athleighs from an assassination attempt by a radical faction.
Carrie Snyder is a prostitute, who is forced out of the fictional southern town of Crebillon, after forming a friendship with a young boy named Paul, whose dying mother is unable to protest against her son visiting such a woman.