A traveler arrives at the Usher mansion to visit his old friend, Roderick Usher. Upon arriving, however, he discovers that Roderick and his sister, Madeline, have been afflicted with a mysterious malady: Roderick's senses have become painfully acute, while Madeline has become nearly catatonic.
In Milan, the beggar Carlone has formed a brotherhood. Carlone's sister Anna, is a poor blind girl. One day Carlone saves a mutilated, who tried to end his days.
A young rogue kills an old lady to rob her. Arrested, he believes it is for this crime, hides nothing from his lawyer, who soon tells him that he is only accused of another theft prior to his crime.
Arizona Ranger Larry Grant is posing as an outlaw while hunting for an outlaw gang, secretly led by Lance Corbin, that is stealing silver in Mexico and smelting it into bars for sale in the United States.