Toru Iwakawa is elected mayor of Takanosu on the platform of improving welfare. With the support of a group formed by residents, he aims to develop a "care town" to stop the isolation of the elderly. However, the town council refuses to support his proposal.
A patient dies beneath Dr. Robert Stenzel's hands. His wife, the virologist Simone, realizes too late that the deceased was carrying a contagious virus.
The Director reflects upon and seeks to understand the causes and the events that lead to her drug-addicted prostitute daughter being murdered at the age of 26.
A technical problem aboard a transatlantic flight forces a plane to land in Porto Santo, the small island of Madeira's archipelago where, according to a legend, Christopher Columbus the 15th century navigator, lived for a while and entertained a sexual relationship with a widow and her nubile daughter.
Grieving the death of his girlfriend, Ashok visits his pal Hemanth. But the journey of healing takes a detour when Ashok begins to fall for Hemanth's devoted wife, Veena, who reminds Ashok of his lost love.
