A writer investigates the suspicious death of his sister at an old Victorian mansion inhabited by her widowed scientist husband on the verge of a breakthrough in dream traveling, an ex-lover from his past, and the doctor she is now in a relationship with.
Lisa is a middle-class white woman from Toronto, Canada. She's also addicted to crack cocaine. To maintain her habit, she works as a prostitute while living in a hotel room.
In the 1920s, former coal miner Harry Hoxsey claimed to have an herbal cure for cancer. Although scoffed at and ultimately banned by the medical establishment, by the 1950s, Hoxsey's formula had been used to treat thousands of patients, who testified to its efficacy.
With detailed assistance from a self-help book -- written by a self-described love guru (Jolina Magdangal) -- Denise (Jennylyn Mercado), a hopeless romantic, finally manages to catch the attention of the man she's had her eye on forever (Mike Tan).