Nasty Baby centers around a Brooklyn couple, Freddy and his boyfriend Mo, who are trying to have a baby with the help of their best friend, Polly. Freddy is an artist, and his latest work is all about babies – it’s clear he’s dying to be a father. Polly is a family practitioner who is more interested in having a baby than having a man. Mo is hesitant about the entire idea, especially when Polly isn’t having success with Freddyʼs sperm and the donor responsibility shifts to him. Set almost entirely in the multicultural vibrancy of Fort Greene, Brooklyn, the trio navigates the idea of creating life, when they are confronted by unexpected harassment from particularly aggressive neighborhood man, nicknamed The Bishop. The Bishop is bothersome in small, yet persistent ways, with a hint of danger. As their clashes become increasingly aggressive, someone is bound to get hurt.
An extremely wealthy elderly man dying from cancer undergoes a radical medical procedure that transfers his consciousness to the body of a healthy young man but everything may not be as good as it seems when he starts to uncover the mystery of the body's origins and the secret organization that will kill to keep its secrets.
Doug Harris is a loveable but socially awkward groom-to-be with a problem: he has no best man. With less than two weeks to go until he marries the girl of his dreams, Doug is referred to Jimmy Callahan, owner and CEO of Best Man, Inc.
Brooklyn mobster and prolific hit man Jimmy Conlon has seen better days. Longtime best friend of a mob boss, Jimmy is haunted by the sins of his past—as well as a dogged police detective who’s been one step behind Jimmy for 30 years.