In 1926, Newt Scamander arrives at the Magical Congress of the United States of America with a magically expanded briefcase, which houses a number of dangerous creatures and their habitats.
Lou Clark, a directionless 26-year-old from the English countryside, takes a job at the local castle as a caregiver and companion to a wealthy young banker, Will Traynor.
Mia, an aspiring actress, serves lattes to movie stars in between auditions and Sebastian, a jazz musician, scrapes by playing cocktail party gigs in dingy bars, but as success mounts they are faced with decisions that begin to fray the fragile fabric of their love affair, and the dreams they worked so hard to maintain in each other threaten to rip them apart.
After his career is destroyed, a brilliant but arrogant surgeon gets a new lease on life when a sorcerer takes him under her wing and trains him to defend the world against evil.
WWII American Army Medic Desmond T. Doss, who served during the Battle of Okinawa, refuses to kill people and becomes the first Conscientious Objector in American history to receive the Congressional Medal of Honor.
Sarah, Gerda and Leonie know each other from the chat room. They meet in a small village and walk together into the woods to commit suicide in a small tent.